Description
This section is directly extracted from the Global Assessment Report: The Analytical and Life Science Instrumentation Industry.
PCR: Nucleic acid amplification, commonly known as polymerase chain reaction (PCR), is one of the most revolutionary developments in modern molecular biology. The technique was introduced in its primitive form in 1986, and has since become an indispensable tool in all laboratories that work with DNA. Today, PCR instruments and reagents have become increasingly sophisticated. PCR enables the detection and amplification of a specific sequence, requiring only a single template to produce millions of copies.
Microarrays: DNA microarrays are the most commonly used, with applications in the detection of DNA sequences (referred to as comparative genomic hybridization or CGH), and the assessment of gene expression. The latter can be used to measure gene expression level, or to compare the relative expression levels between two samples.
Electrophoresis: Electrophoresis has long been an invaluable tool in every biochemistry and molecular biology lab. The technique uses a uniform electric field to separate macromolecules, such as DNA, RNA, proteins, peptides, and their fragments, based on their size and charge.
Capillary Electrophoresis: Capillary electrophoresis is a family of analytical techniques that separate charged molecules based on their electrophoretic mobility through applied voltage. As the development of biologics-based therapeutics grows, so does the need for high-throughput analysis of biomolecules.
SPR and Label-Free Detection: Label-free (LF) detection instruments, or biosensors, are used in basic and applied life science research for the detection or measurement of a biological analyte. The technique converts a biological response into a measurable signal without the aid of fluorescent labels or other tags and tagging agents.
Flow Cytometry: Flow cytometry is becoming increasingly integrated with other life sciences technologies, including NGS applications. Flow cytometers can be integrated into high-throughput robotic workflows, and are ideal for performing single cell analysis. They can even be used to sort cells which have undergone CRISPR/ CAS9 editing. Flow cytometry instruments are no longer just immunological tools, and are now integrated into many areas of life science research.
High Content Analysis/Cell Imaging: High-content analysis, also called high-content screening (HCS) or cellomics, is a high-throughput method of phenotypic screening conducted in cells. HCS systems incorporate automated high resolution digital microscopy, flow cytometry, and analysis software in order to detect changes in cell morphology and/or measure changes in protein synthesis.
Electrophysiology: Electrophysiology is the study of the electrical properties of biological systems. Because electrical impulses are generated by changes in ion concentrations, instruments in this field seek to measure ion flow. Electrophysiology is an important technique in characterizing how cells respond to drugs and drug candidates.
Automated Synthesizers: Automated synthesizer systems, for either oligonucleotides or peptides, are used to automatically build a desired sequence of DNA, RNA, or protein in vitro, without the need for an initial template. These scalable systems can produce quantities of DNA or peptides ranging from micromolar to millimolar in reaction vessels.
In Vivo Animal Imaging: Preclinical studies in animals are carried out before drug candidates are screened in human clinical trials. The use of in vivo imaging is swiftly becoming a standard technique in life science research, used in conjunction with other methods and chemical analyses.
Cell Counters: Automated cell counters provide an accurate, time-saving alternative to manual cell counting methods involving a hemocytometer and microscope, which are tedious and error-prone. These systems are typically employed in cell culture and cell viability assays.
Table of Contents
Life Science Instrumentation
- Introduction and Overview
- The Life Science Instrumentation Market
- Market Size and Forecasts
- Geography
- Life Science Instrumentation Market in US & Canada
- Life Science Instrumentation Market in Europe
- Life Science Instrumentation Market in China
- Life Science Instrumentation Market in Japan
- Life Science Instrumentation Market in India
- Life Science Instrumentation Market in Other Asia Pacific
- Life Science Instrumentation Market in Latin America
- Life Science Instrumentation Market in Rest-of-World
- Life Science Instrumentation Market in Market Share
DNA Sequencing
- Technology Overview
- Key Market Dynamics
- Product Section
- Industry Function
- Gov. Research
- Pharma
- CROs
- Others
- Unit Volume
- Application Sector
- Transcriptome Sequencing
- Metagenomic Sequencing
- Exome Sequencing
- Targeted Sequencing
- Other
- Regional Markets
- Sequencing Markets in US & Canada
- Sequencing Markets in Europe
- Sequencing Markets in China
- Japan
- India
- Other Asia Pacific
- Latin America
- Rest-of-World
- Equipment
- Components
- Aftermarket
- Competitive Situation
- Recent Developments
PCR
- Technology Overview
- Key Market Dynamics
- Product Section
- Real Time PCR
- Traditional
- Digital
- Industry Function
- Unit Volume
- Application Sector
- Regional Markets
- PCR Market in US & Canada
- PCR Market in Europe
- PCR Market in China
- PCR Market in Japan
- PCR Market in India
- PCR Market in Other Asia Pacific
- PCR Market in Latin America
- PCR Market in Rest-of-World
- Equipment
- Components
- Aftermarket
- Competitive Situation
- Recent Developments
Microarrays
- Technology Overview
- Key Market Dynamics
- Product Section
- DNA
- RNA
- Other
- Industry Function
- Unit Volume
- Application Sector
- Regional Markets
- Competitive Situation
- Recent Developments
- US & Canada
- Europe
- China
- Japan
- India
- Other Asia Pacific
- Latin America
- Rest-of-World
- Equipment
- Components
- Aftermarket
Electrophoresis
- Technology Overview
- Key Market Dynamics
- Product Section
- Industry Function
- Unit Volume
- Application Sector
- Regional Markets
- US & Canada
- Europe
- China
- Japan
- India
- Other Asia Pacific
- Latin America
- Rest-of-World
- Equipment
- Components
- Aftermarket
- Competitive Situation
- Recent Developments
Capillary Electrophoresis
- Technology Overview
- Key Market Dynamics
- Product Section
- Benchtop CE
- Microfluidics Based
- Industry Function
- Unit Volume
- Application Sector
- Regional Markets
- US & Canada
- Europe
- China
- Japan
- India
- Other Asia Pacific
- Latin America
- Rest-of-World
- Equipment
- Components
- Aftermarket
- Competitive Situation
- Recent Developments
SPR and Label-Free Detection
- Technology Overview
- Key Market Dynamics
- Product Section
- SPR-Based
- Other LF Detection
- Industry Function
- Unit Volume
- Application Sector
- Regional Markets
- US & Canada
- Europe
- China
- Japan
- India
- Other Asia Pacific
- Latin America
- Rest-of-World
- Equipment
- Components
- Aftermarket
- Competitive Situation
- Recent Developments
Flow Cytometry
- Technology Overview
- Key Market Dynamics
- Product Section
- Analyzer
- Sorter
- Compact FC
- Industry Function
- Unit Volume
- Application Sector
- Regional Markets
- US & Canada
- Europe
- China
- Japan
- India
- Other Asia Pacific
- Latin America
- Rest-of-World
- Equipment
- Components
- Aftermarket
- Competitive Situation
- Recent Developments
High Content Analysis/Cell Imaging
- Technology Overview
- Key Market Dynamics
- Product Section
- Industry Function
- Unit Volume
- Application Sector
- Regional Markets
- US & Canada
- Europe
- China
- Japan
- India
- Other Asia Pacific
- Latin America
- Rest-of-World
- Equipment
- Components
- Aftermarket
- Competitive Situation
- Recent Developments
Electrophysiology
- Technology Overview
- Key Market Dynamics
- Product Section
- Industry Function
- Unit Volume
- Application Sector
- Regional Markets
- US & Canada
- Europe
- China
- Japan
- India
- Other Asia Pacific
- Latin America
- Rest-of-World
- Equipment
- Components
- Aftermarket
- Competitive Situation
- Recent Developments
Automated Synthesizers
- Technology Overview
- Key Market Dynamics
- Product Section
- DNA Synthesis
- Organic Peptide Synthesis
- Industry Function
- Unit Volume
- Application Sector
- Regional Markets
- US & Canada
- Europe
- China
- Japan
- India
- Other Asia Pacific
- Latin America
- Rest-of-World
- Equipment
- Components
- Aftermarket
- Competitive Situation
- Recent Developments
In Vivo Animal Imaging
- Technology Overview
- Key Market Dynamics
- Product Section
- MicroCT
- MicroPET
- MicroMRI
- Optical
- Ultrasound
- MPI
- Industry Function
- Unit Volume
- Application Sector
- Regional Markets
- US & Canada
- Europe
- China
- Japan
- India
- Other Asia Pacific
- Latin America
- Rest-of-World
- Equipment
- Components
- Aftermarket
- Competitive Situation
- Recent Developments
Cell Counters
- Technology Overview
- Key Market Dynamics
- Product Section
- Industry Function
- Unit Volume
- Application Sector
- Regional Markets
- US & Canada
- Europe
- China
- Japan
- India
- Other Asia Pacific
- Latin America
- Rest-of-World
- Equipment
- Components
- Aftermarket
- Competitive Situation
- Recent Developments